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International Immunology 2009 21(6):NP; doi:10.1093/intimm/dxp055
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© The Japanese Society for Immunology. 2009. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

IN THIS ISSUE

The first 10% of the full text of this article appears below.


   Murine mast cells express CRTH2
 
Mast cells are a major source of prostaglandin D2 (PGD2). Here, Boehme et al. (p. 621) show that mouse bone-marrow-derived mast cells express CRTH2 (chemoattractant receptor homologous molecule expressed on Th2 cells) — a PGD2 receptor. Activation of mast-cell CRTH2 triggers signalling, modification of cell surface receptors, and cell migration. The authors suggest a role for PGD2–CRTH2 in allergy.


   Gene expression profiles in mouse models of asthma
 
Genetic backgrounds . . . [Full Text of this Article]


   A role for dopamine in Th2 differentiation
 

   Irradiated CIITA+ tumour cells in anti-tumour vaccination
 

   LPA inhibits NK cell cytotoxicity
 

   Geranylgeranylation in Treg and Th17 cell differentiation
 

   Nitrilase 1 negatively regulates T cells
 

   Prediction of HLA-DQ8-binding T cell epitopes
 

   Bim and IL-7 in B cell lymphopoiesis
 

   Notch 3 and pre-TCR{alpha} co-operate in Tregs
 

   FDC IL-6 mediates optimal B cell responses
 

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