International Immunology 2009 21(4):NP; doi:10.1093/intimm/dxp036
© The Japanese Society for Immunology. 2009. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org
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Innate immunity in Japan: a historical perspective
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In this article,
Kaisho and Takeda (p. 313) outline the history
of research into innate immunity in Japan. They highlight the
many crucial contributions made by Japanese scientists to the
field, specifically describing phagocytic cells and innate immune
responses in cancer. Finally, they highlight the importance
of research in Japan to the burgeoning topic of Toll-like receptors.
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Innate immunity: an update on TLRs, RLRs and NLRs in pathogen recognition
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Here,
Kawai and Akira (p. 317) provide a state-of-the-art review
on three types of pattern-recognition receptor (PRR): Toll-like
receptors (TLRs), retinoic acid-inducible gene-I-like receptors
(RLRs) and nucleotide-binding oligomerization domain-like receptors
(NLRs).
. . . [Full Text of this Article]
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Bcl-3 inhibits T cell activation and death
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Immunization with DNase II leads to DNase and RNase activity
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GM-CSF enables DCs to produce retinoic acid
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Transplantation tolerance induced by selective Treg expansion
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MEKK3 is crucial for T cell function and development
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A role for c-Abl in peripheral B cell functions
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Natural and pathologic antibodies against topoisomerase I
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LFA-1-independent NK cell anti-fungal activity
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Responses to NF-L in multiple sclerosis
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Recirculating T cells express L-selectin cyclically
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Fra-1 regulates LPS-mediated responses
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Stromal cell lymphotoxin βR signalling
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TRAF2 and TRAF3 are both important for CD40 signalling
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