International Immunology 2009 21(1):NP; doi:10.1093/intimm/dxn138
© The Japanese Society for Immunology. 2009. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org
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CRTH2 antagonism blocks skin inflammation
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Here,
Boehme et al. (p. 1) examine ovalbumin-induced murine
atopic dermatitis treated with an antagonist of CRTH2 (chemoattractant
receptor homologous molecule expressed on T
h2 cells) —
one of the PGD
2 receptors —and show decreased cutaneous
inflammation and antigen-specific antibody production, suggesting
a pivotal role for this receptor. The authors then describe
. . . [Full Text of this Article]
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F. novicida disrupts STAT1 signalling
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 c cytokines and survival of CD127+ T cells
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The B-1 cell repertoire is determined by the pre-BCR
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Two phenotypes of melanoma-specific T cells expand in vitro
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Immunodominant epitopes of SARS
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IFN- and IL-6 control superantigen-mediated T cell death
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FITC-induced skin inflammation requires CRTH2
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Substrate recognition by human chymase
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