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International Immunology, Vol 10, 711-717, Copyright © 1998 by Oxford University Press

ARTICLES

Immune information, self-organization and meaning

H Atlan and IR Cohen
The Human Biology Research Center, Hadassah University Hospital, Ein Kerem, Jerusalem, Israel.

To effect the molecular integrity of the individual, the immune system has to gather antigenic information and respond in a meaningful way. Immunologists traditionally have focused their research on analyzing the component parts of the system. The achievements of immunology in its analytical enterprise have now made it possible to begin the task of synthesis. In this paper, we shall consider how the immune system combines germline and somatic information using a chemical language to establish the functional meaning of antigens.
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